New Genetic Mutation Discovered to Halt Lupus Development
Written by WTJ on January 18, 2008 – 2:17 pm -The Scripps Research scientists found the mutation on a single genetic locus-the position of a gene on a chromosome-called Lmb3 that plays a major role in modulating autoimmunity in transgenic mice. The cloned version of the Lmb3 mutation resulted in developmental and functional alterations in T cells, including reduced migration, survival, and activation. The study also showed that the Lmb3 autoimmune-suppressing phenotype could be transmitted only through Coro1aLmb3 T cells.
Lupus is in my family gene, just like diabetes, high blood pressure, cholesterol, etc. It’s just the matter of time. A curse huh? At least we die slowly.
After reading “Should Children Be Permitted To Get Genetic Testing For BRCA 1/2 Mutations?” from ScienceDaily yesterday, my answer would be a “YES”. In my opinion, prevention is always better than curing. If I have children, I would give them a genetic testing just for their sake.
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Tags: genetic, genetic disease, genetic testing, Lmb3, lupus, mutation, scripps research, scripps research institute |
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