Nerdy Science Blog

A clinically available and well-tolerated drug, sodium phenylbutyrate, currently used to treat patients with alterations in the urea cycle may be an alternative drug to Alzheimer’s disease and other similar dementias.  Researchers from Center for Applied Medical Research (CIMA) of the University of Navarra showed the improvement of memory of laboratory mouse with Alzheimer’s disease.  It was thought that the drug made the neuron connection proteins easier to fuse, thus increasing the learning capacity of the mice.  It is said that sodium phenylbutyrate could act more effectively in shorter period of time in Alzheimer’s patients than other drugs.  The results were published in the journal Neuropsychopharmacology.  Currently the researchers are looking into the acting mechanism of the drug.  Please consult your doctor before you try taking the drug.

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