Posts Tagged ‘PXK’
Environmental Factors Cause Lupus?
Written by WTJ on January 21, 2008 – 2:03 pm -Systemic lupus can involve the joints, kidneys, heart, lungs, brain and blood. The disease occurs in about 31 out of every 100,000 people and affects women nine times more frequently than men. Scientists believe that lupus is caused by genetic variants that interact with each other and the environment.
The scientists found evidence of an association with multiple SNPs in three genes: ITGAM, KIAA1542 and PXK, and also at SNP rs10798269, which is not within any known gene. ITGAM is important for both the adherence of immune cells and for cleaning up pathogens. KIAA1542 is important for translating the DNA code into proteins. PXK encodes a molecule that transmits signals and controls complex processes in cells. These scientists also found association in genes previously associated with lupus and other autoimmune diseases.
Guess we need to change our lifestyle to prevent lupus. I read an interesting sentence from somewhere (I can’t remember where), it said like this, “If you won’t die because of heart disease today, you’re likely to die because of cancer.” How true.
Tags: genes, genetic disease, genetic disorder, immune system, ITGAM, KIAA1542, lupus, PXK, SLEGEN, SNP rs10798269, SNPs
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