Posts Tagged ‘Rockefeller University’
Western Diets Increase The Risk of Colon Cancer
Written by WTJ on January 2, 2010 – 2:00 pm -
A team of researchers at Rockefeller University found that Western diet, which is high in fat, and low in fiber, vitamin D and calcium, is associated with colorectal cancer.
Researchers found that high fat diets induce inflammatory response in mice colon, and such inflammation could be the cause for carcinogenesis in mice colon. Carcinogenic process is a process normal cells are transformed into cancer cells. High fat diets will induce oxidative stress and alter immune responses, and this will eventually increases the risk of colorectal cancer.
The result was published in November 2009 issue of The Journal of Nutrition.
Colon cancer is a deadly disease that affects millions of people around the world today and appears to be the third most common form of cancer worldwide. There are also evidence shows that consumption of red meat, processed meat and alcohol are also likely to increase the risk of colorectal cancer.
Tags: calcimum, cancer, carcinogenesis, carcinogenic process, colon, colon cancer, colorectal cancer, diet, Fat, fiber, high fat, immune response, inflammation, inflammatory response, nutrition, peter holt, Rockefeller University, The Journal of Nutrition, vitamin d, western diet
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Protein Links to Stress and Depression
Written by WTJ on March 1, 2009 – 10:47 am -
Recent studies showed that a protein called kainate receptors response to certain antidepressants, and the protein also involved in depression and suicidal thought.
Scientists at Rockefeller University examined one of the five subunits of kainate receptors, KA1 in rats and the result may help to explain the mechanism of the protein reshaping the brain in response to stress. Researchers at Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at Rockefeller University studied the impact of stress and steroid on rats. They induce stress to the rats by restraining them 6 hours per day for over three weeks. The production of KA1 in these rats increased in certain parts of hippocampus under the instruction sent by messenger RNA. Hippocampus involved in learning and memory functions. Scientists also tried to inject hormone called corticosteroids into the unstressed rats. Low dose of corticosteroids increased KA1 production but high dose did not.
Fortunately the brains will replace the retracted neurons once the stress is removed. The study was published in the journal PLos ONE. The authors were Richard G. Hunter, Rudy Bellani, Erik Bloss, Ana Costa, Katharine McCarthy, and Bruce S. McEwen.
Tags: adaptive plasticity, Ana Costa, Bruce S. McEwen, corticosteroid, depression, Erik Bloss, Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, hippocampal kainate receptor, hippocampus, HPA, KA1, kainate receptor, Katharine McCarthy, mental health, PLoS ONE, psychology, Richard G. Hunter, richard hunter, Rockefeller University, Rudy Bellani, Steroid, stress
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